Education
Educational Qualifications
B.Sc

-1984

Institute of Science (Nagpur , Maharashtra, India)

M.Sc

-1986

Department of Biochemistry (Nagpur , Maharashtra, India)

Ph.D

-1994

Institute of Microbial Technology (Chandigarh, Chandigarh, India)

Professional Experience
Senior Demonstrator

1995 -to- 1999

Department of Experimental Medicine & Biotechnology

Responsibilites:
Research Associate

1999 -to- 2005

Department of Experimental Medicine & Biotechnology

Responsibilites:
Reader

2005 -to- 2008

Department of Biochemistry, Panjab University

Responsibilites: TEACHING
Associate Professor

2008 -to- 2011

Department of Biochemistry, Panjab University

Responsibilites: TEACHING
Professor

2011 -to- Till Now

Department of Biochemistry, Panjab University

Responsibilites: TEACHING
Achievements
Awards & Honours
4 th Prize :“Cytotoxic T Lymphocyte Activity In The Pathogenesis Of Systemic Lupus Erythematosus” Dilip Shah, Archana Bhatnagar, Ajay Wanchu at International forum “Excellence in Rheumatology” conference held in Turkey

in 2011

1 st Prize “Oxidative stress studies in different tissues of experimental mouse model of lupus” at National Symposium on Animal Remodelling: From laboratory to Clinic held at PGIMER, Chandigarh

in 2009

Awarded CSIR/ UGC fellowship for carrying out research towards Ph.D. degree

in 1986

Awarded gold medals (two) for proficiency in M.Sc. Biochemistry, Nagpur University, Nagpur

in 1986

Awarded gold medals in Zoology and Botany each and a Chemistry cash prize for obtaining highest marks in B.Sc., Nagpur University, Nagpur

in 1984

Workshops/Training
Attended a Refresher Course

on The Evergreen Catalyst, Course in Biological Sciences, The Evergreen Catalyst, organized by Dept. of Zoology, PU, Chandigarh,
in 2011 for 1 Day

Books/Chapters of Book Published
Cytokines in Pancreatitis. Archana Bhatnagar and J.D.Wig The Pancreas (Published by Azad Offset Printers, Chandigarh, India)

Authors: 2

Oxidative stress: A major player in the pathophysiology of Systemic Lupus Erythematosus. Ashish Aggarwal and Archana Bhatnagar. Systems Biology of Free Radicals and Anti-oxidants (Springer-Verlag Berlin Heidelberg 2014). In press.

Authors: 2

Pulmonary infections- Oxidant injury & role of antioxidants. Leishangthem Bidyalaxmi Devi, Ruchi Rastogi and Archana Bhatnagar. Studies on Respiratory Disorders. (Series: Oxidative Stress in Applied Basic Research and Clinical Practice, Springer Science a

Authors: 3

Research Paper/Articles Published
Role of cytolytic impairment of natural killer and natural killer T-cell populations in rheumatoid arthritis.

Journal: Clin Rheumatol. 2014 May 7.

Authors: 3

Fish oil suppresses cell growth and metastatic potential by regulating PTEN and NF-κB signaling in colorectal cancer.

Journal: Plos One. 2014 Jan 8;9(1):e84627.

Authors: 3

A study on the association of auto antibodies, chemokine and its receptor with disease activity in Systemic lupus erythematosus in North Indian population.

Journal: Rheumatol Int. 2013 Nov;33(11):2819-26.

Authors: 4

Size Tunable Green Synthesis of Silver Nanoparticles using Trachyspermum ammi (Ajwain) and their effect on a B Cell Line.

Journal: Journal of Nanoengineering and Nanomanufacturing 3,2 (2013) 154-161

Authors: 3

Alteration in apoptosis and cell cycle by celecoxib and/or fish oil in 7,12-dimethyl benzene (α) anthracene-induced mammary carcinogenesis.

Journal: Tumor Biol. (2013) 34 (6):3753–3764.

Authors: 4

Alterations in mitochondrial membrane in chemopreventive action of fish oil.

Journal: Cancer Invest 31, 231-40.

Authors: 5

Bi(o)communications among peripheral blood fractions: A focus on NK and NKT cell biology in rheumatoid arthritis.

Journal: Autoimmunity 46, 238-50.

Authors: 3

Altered redox state and apoptosis in the pathogenesis of systemic lupus erythematosus.

Journal: Immunobiology 218, 620-7.

Authors: 4

NK cell depletion and its relation to elevated redox potential in rheumatoid arthritis

Journal: Rheumatology 51(suppl 1): i34-i35

Authors: 3

Impaired NK and NKT cells immunobiology in rheumatoid arthritis.

Journal: Journal of Translational Medicine 10(Suppl 3):P32.

Authors: 3

Therapeutic effect of Withania somnifera on pristane-induced model of SLE.

Journal: Inflammopharmacology 20, 195-205.

Authors: 3

Prophylactic versus therapeutic effect of Withania somnifera on pristane induced peritoneal inflammation in female Balb/c mice.

Journal: Pharmacology online 1, 510-517.

Authors: 2

Role of reactive intermediates in the immunopathogenesis of the pristane-induced Balb/c model of lupus.

Journal: Lupus 20, 1421-1425.

Authors: 3

Prophylactic effect of Withania somnifera on inflammation in a non-autoimmune prone murine model of lupus.

Journal: Drug Discov Ther 5, 195-201.

Authors: 3

Association between T lymphocyte sub-sets apoptosis and peripheral blood mononuclear cells oxidative stress in systemic lupus erythematosus.

Journal: Free Radic Res 45, 559-567.

Authors: 5

Soluble granzyme B and cytotoxic T lymphocyte activity in the pathogenesis of systemic lupus erythematosus.

Journal: Cell Immunol 269, 16-21.

Authors: 4

Interaction between oxidative stress and chemokines: possible pathogenic role in systemic lupus erythematosus and rheumatoid arthritis.

Journal: Immunobiology 216, 1010-1017.

Authors: 3

Interplay of cytokines and chemokines in the pathogenesis of Systemic Lupus Erythematosus.

Journal: American Journal of Immunology 7, 29-38.

Authors: 3

Oxidative stress in systemic lupus erythematosus: relationship to Th1 cytokine and disease activity.

Journal: Immunol Lett 129, 7-12.

Authors: 3

Relationship between T lymphocyte subsets and cortisol in systemic lupus erythematosus.

Journal: Kathmandu Univ Med J (KUMJ) 7, 213-219.

Authors: 4

Invited Lectures and Chairperson-ships
Attended Annual Meeting about Phagocytosis by PBMC: A flowcytometry based investigation

on The 4th Annual meeting of TCS at Panjab University & PGIMER, Chandigarh.

Attended International Conference on free radicals, inflammation and antioxidants in diseases.

on Prof. M.C. Nath Memorial lecture 2011 , organized by Department of Biochemistry & Biotechnology, Dr. Ambedkar College, Shivaji Science college & Sindhu M on 2011-01-13

Invited for Lecture

on Lecture on Flow cytometry , organized by Department of Biotechnology, PU, Chandigarh on 2010-11-23

Chaired a Session

on Molecular Cardiology held at International Society of Heart Research. , organized by Department of Experimental medicine and biotechnology and Cardiology on 2008-03-29

In Media
Radio talk delivered on Scope of biochemistry for the programme “ Shiksha ke anek aayam” aired on Jyotirgamaya: 91.2 MHz - Panjab University Community Radio Station.
Others
Research Interest: To understand biochemical mechanisms associated with oxidative stress and immune system in autoimmune disorders like systemic lupus erythematosus, rheumatoid arthritis and celiac disease; which may, in future, lead to identification of sites for therapeutic intervention. There have been some interesting observations that provide hope regarding prediction of disease severity on basis of a set of tests and their analyses.
Research Interest: Immunobiology of cancer where immune manipulations might alter the balance between growth and elimination of tumor. Analyses of such intra-tumor immune activities in animal model are being studied to search for predictive/ prognostic immune signatures.
Research Interest: Correction of autoimmune disorders and tumors by immunomodulation using natural products (example Withania somnifera) in animal models.
Research Interest: Synthesis of nanoparticles by a “green” route, giving green nanoparticles of diverse morphologies for their effects on cellular systems.
Grants Received: Have successfully completed projects funded by University Grants Commission, Council of Scientific and Industrial Research, Indian Council of Medical Research, Union Territory- Department of Science & Technology.
Holder of Chief Minister’s fellowship of merit (1979) and National Merit Scholarship (1980).
Research Scientist, Eijkman - Winkler Institute, UMC, Utrecht, The Netherlands in the year of 2001
Research Scientist, German Research Center for Biotechnology, Braunschweig, Germany in the year of 2001
Project Work
Professional Association
Member, Association of Clinical Biochemistry of India
Member, Indian Immunology Society
Member, The Indian Society of Human Genetics
Member, The Cytometry Society of India
Member, Indian Science Congress Association
Member, International Society for Heart Research