Education
Educational Qualifications
B.Sc

Punjab University (Chandigarh, Chandigarh, India)

M.Sc

aligarh Muslim University (Aligarh , Uttar Pradesh, India)

Professional Experience
Emeritus Fellow (UGC)

2011 -to- 2012

Department of Biochemistry, Panjab University

Responsibilites:
Professor

Department of Biochemistry, Panjab University

Responsibilites:
Reader

1985 -to- 1996

Department of Biochemistry, Panjab University

Responsibilites:
Assistant Professor

1978 -to- 1981

Post Graduate Institute of Medical Education And Research (PGIMER)

Responsibilites:
Pool Officer (CSIR)

1977 -to- 1978

Post Graduate Institute of Medical Education And Research (PGIMER)

Responsibilites:
Research Assistant

1971 -to- 1972

Post Graduate Institute of Medical Education And Research (PGIMER)

Responsibilites:
Lecturer

1967 -to- 1970

Haryana Agricultural University

Responsibilites:
Junior Research Fellow

Department of Chemistry, Muslim University

Responsibilites:
Dean (Faculty of Science)

2006 -to- 2008

Panjab University

Responsibilites:
Director

Central Instrumentation Laboratory/SAIF, Panjab University, Chandigarh

Responsibilites:
Achievements
Awards & Honours
Awarded J.Mitra Memorial Award by Indian Society of Gastroenterology: 2006.

in 2006

Effect of pesticides on intestinal brush border membrane structure and function. Financed by CSIR, New Delhi (1979)

in 1979

Effect of Organochlorine pesticides on intestinal physiology in certain nutritional deficiencies. ICMR, New Delhi (1980-83).

in 1983

Biochemical lesions in blood and in selected tissues of rhesus monkeys exposed to certain pesticides. Department of Science & Technology, New Delhi (1981-84).

in 1984

Functional role of surface oligosaccharides in intestinal microvillus membrane. ICMR, New Delhi (1985-88).

in 1988

Effect of maternal nutrition on surface oligosaccharides in developing rat intestine. ICMR, New Delhi (1987-90).

in 1990

Studies on the molecular mechanisms of mal-absorption in experimental animals. ICMR, New Delhi (1989-92).

in 1992

Effect of ethanol on the expression of brush border enzymes and transport proteins in rat small intestine. CSIR, New Delhi (1995-98).

in 1998

Expression of enzyme and transport proteins in intestine of animals induced for malabsorption, ICMR, New Delhi (1995-98).

in 1998

Effect of prenatal exposure of ethanol on functional development of intestine in rats. ICMR, New Delhi (2001-04).

in 2004

Studies on intestinal glycosylation in chronic ethanol exposed rats. UGC, New Delhi (2003-06).

in 2006

Role of polyphenols as antioxidants in the turn over of epithelial cells in rat small intestine. UGC. New Delhi (2011-12)

in 2012

Research Paper/Articles Published
Effect of scurvy on intestinal transport of methionine.

Journal: Indian J Biochem (1970) 7: 209-210.

Authors: 2

Effect of hormonal treatments in rats on the intestinal transport of methionine.

Journal: Indian J Exp Biol (1970) 8: 330-331.

Authors: 3

Uber die wirkung des alloxan diabetes von insulin and diabetogenen hormonen (thyroxin hydrocortisone and oxytocin) and intestinalen transport non-glycin.

Journal: Z Gastroenterol (1971), 9: 425-428.

Authors: 2

In vitro studies on the intestinal transport of glycine in scorbutic guinea pigs.

Journal: Ind J Exp Biol (1972), 10: 237-339.

Authors: 2

Effect of cycloheximide on intestinal transport of methionine and glycine.

Journal: Indian J Exp Biol (1972) 10: 233-234.

Authors: 1

Effect of alloxan diabetes, insulin and diabetogenic hormones on intestinal transport of glycine in vitro.

Journal: Indian J Exp Biol (1972), 10: 237-238.

Authors: 2

Studies on intestinal Na, K-ATPase Effect of Cycloheximide and Puromycin.

Journal: Indian J Biochem Biophys (1972): 206-207.

Authors: 2

Distribution of Na, K-ATPase in rat intestine.

Journal: Indian J Biochem Biophys (1972), 9: 279-280.

Authors: 3

Co-transport of organic solutes and Na ions in small intestine. Amino acid transport – I.

Journal: Biochemistry , USA (1974) 13: 2882-2890.

Authors: 2

The activation of intestinal brush border sucrase by alkali metal ions: An allosteric mechanism similar to that for the Na-activation of non-electrolyte transport systems in intestine.

Journal: Arch Biochem Biophys (1975) 168: 585-593.

Authors: 2

Harmaline interactions with Na-binding sites in intestinal brush border sucrase.

Journal: Biochim Biophys Acta (1977), 483: 367-374.

Authors: 2

Effect of chronic alloxan diabetes and insulin administration on intestinal brush border enzymes.

Journal: Experientia (1978) 34: 741-742.

Authors: 3

Effect of DDT (Chlorophenotane) administration on glucose uptake and brush border enzymes in monkey intestine.

Journal: Acta Pharmacol Toxicol (1978) 43: 99-102.

Authors: 3

pH dependent effects of alkali metal ions on intestinal brush border sucrase.

Journal: J Biol Chem (1979) 254: 9534-9541.

Authors: 2

Lipid composition of monkey intestinal brush border membrane: Effect of DDT.

Journal: Indian J Biochem Biophys (1979) 16: 175-177.

Authors: 4

Effect of chronic hypo and hypervitaminosis C on intestinal uptake of glucose and alanine.

Journal: Experientia (1979) 35: 1057-1058.

Authors: 4

Zinc uptake by rat intestine in vitro and its interactions with cadmium and chromium.

Journal: Indian J Biochem Biophys (1979) 16: 80-83.

Authors: 3

Alterations in the structure and functions of intestinal brush border membrane in chronic DDT exposed monkeys.

Journal: Pest Biochem Physiol (1979) 12: 141-146.

Authors: 5

Inhibition of D-glucose uptake by zinc in rat intestine.

Journal: Biochem Med (1979) 22: 192-197.

Authors: 3

Characterization of Ca-ATPase activity in S. griseus.

Journal: J Gen Microbiol (1979) 112: 393-395.

Authors: 4

Quantitative analysis of the mixed effects of alkali metal ions on intestinal brush border sucrase.

Journal: Biochim Biophys Acta (1980) 613: 140-152.

Authors: 4

Effect of DDT (Chlorophenotane) administration on lipid metabolism of intestinal epithelium of rhesus monkeys.

Journal: Indian J Exp Biol (1980) 18: 660-661.

Authors: 5

Effect of a single oral dose of melathione on D-glucose and glycine uptake and on brush border enzymes in rats.

Journal: Toxicol Letters (1980) 6: 411-415.

Authors: 4

Effect of undernutrition on lipid metabolism of lung: In vivo incorporation of labelled glucose into lipids.

Journal: Biochem Medicine (1980) 24: 268-273.

Authors: 4

Intestinal brush border membrane structure and function: Effect of early postnatal under nutrition.

Journal: Pediatric Res (1981) 15: 112-115.

Authors: 4

Effect of folate deficiency on digestive and absorptive functions of intestinal epithelium in rats.

Journal: Acta Vitaminol Enzymol (1981) 3: 12-16.

Authors: 3

Effect of single oral dose of DDT on intestinal uptake of nutrients and brush border enzymes in protein calorie malnourished monkeys.

Journal: Pest Biochem Physiol (1981) 15: 143-148.

Authors: 3

Changes in the chemical composition of intestinal brush border membrane in alloxan induced chronic diabetes.

Journal: Indian J Exp Biol (1981) 19: 503-505.

Authors: 4

Effect of vitamin C deficiency in guinea pigs on intestinal functions and chemical composition of brush border membranes.

Journal: Ann Nutr Metabol (1981) 25: 213-220.

Authors: 6

A comparative study of the digestive and absorptive functions of rat intestine: Effect of various types of jaundice.

Journal: Ind J Med Res (1981) 74: 97-101.

Authors: 5

Effect of thyroxine on trapnsport and metabolic functions of the small intestine in albino rats.

Journal: Ind J Med Res (1981) 74: 85-90.

Authors: 4

Solubilisation of sucrase and alkaline phosphatase using papain and detergents from microvillus membranes of guinea pig intestine.

Journal: Ind J Biochem Biophys (1981) 18: 198-201.

Authors: 2

Effect of vitamin B6 deficiency on intestinal absorption and excretion of oxalate in rats.

Journal: Urolithiasis; Clinical and basic research (Eds. Smith et al) plenum Press New York. (1981) pp 783-787

Authors: 4

Actue dieldrin toxicity: Effect on the uptake of glucose and leucine and on brush border enzymes in monkeys intestine.

Journal: Chemico-biol Interaction (1981) 37: 165-170.

Authors: 5

Transport of zinc in vitro during growth and development in rats.

Journal: Ind J Biochem Biophys (1981) 18: 430-433.

Authors: 5

Pathogenesis of malabsorption in infection with giardia lamblia. Proceedings Ist Asian Conference on Diarrhoeal diseases.

Journal: Decca (1981) pp 66- 74.

Authors: 2

Intestinal uptake of nutrients and brush border enzymes in normal and thymectomised giardia lamblia infected mice.

Journal: Ind J Med Res (1982) 75: 33-39.

Authors: 4

Alterations in the activities of intestinal enzymes in vitamin C deficient guinea pigs.

Journal: Enzyme (1982) 27: 75- 80.

Authors: 5

Transport studies and enzyme assays in giardia lamblia infected mice.

Journal: Trans Royal Sco Trop Med Hyg (1982) 76: 616-619.

Authors: 2

Structure and function of intestinal brush border membrane: Effect of chronic vitamin C deficiency in guinea pigs.

Journal: Biochem Med (1982) 27: 325-333.

Authors: 4

Effect of a single oral dose of p-pDDT on the absorption of nutrients in vitro and on brush border enzymes in rat intestine.

Journal: Arch Toxicol (1982) 49: 131-138.

Authors: 2

Effect of a single oral dose of endosulfan on intestinal uptake of nutrients and on enzymes in rats.

Journal: Toxicol Letter (1982) 12: 7-12.

Authors: 4

Alteration in intestinal functions in response to thyroxine and cortisone administrations in undernourished rats.

Journal: Ann Nutr Metabol (1982) 26: 331-337.

Authors: 4

Effect of a single oral dose of DDT on lipid metabolism in protein calorie mannourished rhesus monkeys.

Journal: Ind J Biochem Biophys (1982) 19: 111-114.

Authors: 5

Effect of hypo and hypervitaminosis C on oxalate absorption in guinea pigs.

Journal: Acta Vitaminol Enzymol (1982) 5: 235-241.

Authors: 4

Isatin: An inhibitor of D- glucose uptake in rat intestine.

Journal: Biochem Med Metabol Biol (1983) 29: 46-50.

Authors: 3

Postnatal changes in lectin binding to microvillus membranes from rat intestine.

Journal: Biochem Biophys Res Comm (1983) 113: 400-406.

Authors: 2

Effect of dietary thiamine deficiency on intestinal functions in rats.

Journal: Am J Clin Nutr (1984) 40 226-234.

Authors: 3

Subcrhronic melathion treatment effects on rat intestinal functions.

Journal: Bull Environ Contam Toxicol (1984) 33: 289-294.

Authors: 5

Effect of vitamin B6 deficiency on intestinal absorption of Calcium and oxalate in rats.

Journal: Biochem Med Metaboil Biol (1984) 32: 34-42.

Authors: 4

Pinedo R: Intestinal transport of manganese from human milk, bovine milk and infant formula in rats.

Journal: Life Sciences (1984) 35: 2415-2419.

Authors: 5

Lymphocytes proliferation and intestinal functions in mice infected with giardia lamblia.

Journal: Indian J Med Res (1984) 80: 159-163.

Authors: 4

Postnatal changes in biosynthesis of microvillus membrane glycans of rat small intestine I: Evidence of a shift from terminal sialylation to fucosylation.

Journal: Biochem Biophys Res Comm (1984) 125: 546-553.

Authors: 2

Evidence of an increased intestinal absorption of oxalate in rats induced for bladder stones.

Journal: Indian J Exp Biol (1984) 22: 555-556.

Authors: 4

Comparative studies on the effect of single oral dose of DDT and malathion on intestinal uptake of nutrients and brush border enzymes in guinea pigs.

Journal: Indan J Gastroenterol (1984) 3: 151-154.

Authors: 5

Effect of maleic acid on the intestinal uptake of calcium and oxalate in pyridoxine deficiency. In Urolithiasis related clinical Research. (Eds. Schivillie et al).

Journal: Plenum Press, New York (1985) pp 155-159.

Authors: 2

Inhibition of Dglucose uptake by isatin: Effect of harmaline and various SH reagents.

Journal: Biochem Med Metabol Biol (1985) 34: 207-213.

Authors: 6

Differential toxicity of ricin to rabbit intestinal epithelium in relation to postnatal maturation.

Journal: Pediatric Res (1985) 19: 868-872.

Authors: 5

Effect of dietary pyridoxine deficiency on intestinal functions in rats.

Journal: Nutr Res (1985) 5: 299-304.

Authors: 3

Effect of hormone administration on sialylation and fucosylation of intestinal microvillus membranes in rats.

Journal: Pediatric Res (1985) 19: 899- 902.

Authors: 2

Effect of pH on Na-stimulated Dglucose uptake in rat intestine.

Journal: Indian J Biochem Biophys (1986) 23: 212-214.

Authors: 4

Age related changes in sialylation and fucosylation of epithelial cell surface. Hormonal effects. In Ion Gradient coupled Transport (Eds Alvarado F & Van Os CH) Elsevier Science Publishers,

Journal: Amsterdam. (1986) pp 375-379

Authors: 3

Temperature induced changes in brush border lactase and alkaline phosphatase activities of developing rat intestine.

Journal: Indian J Exp Biol (1986) 24: 760-762.

Authors: 3

Changes in sialic acid and fucose contents of enterocytes across crypt - villus axis of developing rat intestine.

Journal: Biochem Med Metabol Biol (1988) 39: 105-112.

Authors: 3

Effect of surface desialylation on intestinal uptake of proteins in suckling rat intestine.

Journal: Indian J Exp Biol (1988) 26: 31-34.

Authors: 4

Hormone induced changes in sialic acid and fucose contents of enterocytes across crypt-villus axis in rat intestine.

Journal: Indian J Med Res (1988) 87: 303-307.

Authors: 4

pH dependent glycine uptake in presence and absence of Na ions from rat small intestine.

Journal: Biochem Med Metabol Biol (1988) 40: 118-122.

Authors: 4

Effect of hormones on the development of various brush border enzymes across crypt-villus axis in rat intestine.

Journal: Indian J Med Res (1988), 88: 169-174.

Authors: 5

Fucose and sialic acid contents of intestinal microvillus membranes from various animal species.

Journal: Indian J Exp Biol (1989) 27: 20-22.

Authors: 4

Intestinal absorption of macromolecules in suckling rats nursed on mothers fed low protein diet.

Journal: Biol Neonate (1990), 58: 104- 111.

Authors: 4

Effect of under-nutrition and hormone treatments on the absorption of proteins in suckling rat intestine.

Journal: Biochem Med Metabol Biol (1990) 43: 45-52.

Authors: 3

Kinetic properties of gama - glutamyl-transpeptidase and leucine amino-peptidase in developing rat intestine.

Journal: Indian J Exp Biol (1990) 28: 18-22.

Authors: 3

Kinetic characteristics of brush border alkaline phosphatase and sucrase in developing rat intestine.

Journal: Indian J Biochem Biophys (1990) 27:88-92.

Authors: 2

Effect of malnutrition and hormone treatments on intestinal microvillus membrane glycosylation in suckling rats.

Journal: Ann Nutr Metabol (1990) 34: 155-162.

Authors: 3

Maternal nutrition and development of intestinal functions II: Effect of feeding high protein and high fat diets to lactating rats.

Journal: Indian J Exp Biol (1990) 28: 276-279.

Authors: 3

pH dependent inhibitory effects of tris and Li ions on intestinal brush border sucrase.

Journal: J Enzyme Inhibition (1990), 4: 15-26.

Authors: 5

Effect of various doses of medoxyprogesterone acetate on intestinal functions in rats.

Journal: Indian J Gastroenterol (1990) 9: 45-48.

Authors: 3

Rat intestinal alkaline phosphatase secretion into lumen and serum is co-ordinately regulated.

Journal: Biochim Biophys Acta (1991) 1091: 1-8.

Authors: 3

Effect of maternal nutrition on epithelial cell surface glycosylation in suckling rat intestine.

Journal: In Bio membranes Health & Diseases ( Vol I, pp 93-98).

Authors: 4

Effect of EGF on microvillus membrane functions in suckling rat intestine.

Journal: Bio membranes Health & Disease.Vol I, pp 87-91.

Authors: 2

Intestinal epithelial cell surface glycosylation in mice : I Effect of low protein diet.

Journal: Ann Nutr Metabol (1992) 36: 71-78.

Authors: 3

Effect of chronic ethanol feeding on microvillus membrane glycosylation in normal and protein malnourished rat intestine.

Journal: Nutr (1992), 87: 338-342.

Authors: 4

Effect of divalent metal ions on soluble and membrane bound alkaline phosphatase activity in suckling rat intestine.

Journal: Indian J Exp Biol (1992), 30: 685-689.

Authors: 2

Intestinal epithelial cell surface glycosylation in mice II: Effect of high protein diet.

Journal: Ann Nutr Metabol (1992), 36: 288-295.

Authors: 2

CaCO2 cell transfection by rat intestinal cDNA increases surfactant like particles.

Journal: Am J Physiol (1992) 263: G 756-76 6.

Authors: 6

Characterization of proteins in rat and human intestinal surfactant like particles.

Journal: Arch Biochem Biophys (1993) 300: 280-286.

Authors: 4

Isatin: An inhibitor of acetylocholine esterase activity in rat brain.

Journal: Biogenic Amines (1993), 9: 281-289.

Authors: 3

Effect of feeding high fiber diet on mice intestinal brush border membrane composition.

Journal: Indian J Exp Biol (1993) 31: 136-139.

Authors: 4

Effect of Feeding high fat high fiber diet on brush border membrane enzymes in mice intestine.

Journal: Indian J Med Res (1993), 98: 136-142.

Authors: 3

Effect of pH and sodium ions on intestinal uptake of lysine in rats.

Journal: Indian J Exp Biol (1993), 31: 529-532.

Authors: 3

Effect of chronic ethanol administration on absorptive functions of rat small intestine.

Journal: Alcohol (1993), 10: 299-302.

Authors: 4

A possible role of rat surfactant like particles in Trans- epithelial triacylglycerol transport.

Journal: J Clin Invest (1994) 93: 70-80.

Authors: 6

Effect of chronic ethanol administration on intestinal microvillus membrane glycosylation in rats fed pellet diet and protein rich diet.

Journal: J Clin Biochem Nutr (1994) 16: 133-142.

Authors: 5

The secretion of intestinal alkaline phosphatase from the enterocytes.

Journal: J Gasteroenterol (1994), 29: 63-67.

Authors: 5

Inhibition of rabbit brush border sucrase by indoline 2,3 dione (Isatin) at pH 5.0

Journal: Indian J Biochem Biophys (1994) 31: 191-194.

Authors: 4

Inhibition of brush border sucrase by isatin in rat intestine.

Journal: Indian J Exp Biol (1994), 37: 612-615.

Authors: 4

Effect of ethanol administration together with high or low protein diets on lipid composition of intestinal microvillus membranes in rats.

Journal: J Clin Biochem Nutr (1994), 16: 167-175

Authors: 5

Effect of dietary fat and chronic ethanol administration on intestinal uptake of solutes in rats.

Journal: J Clin Biochem Nutr (1994), 17: 46- 54.

Authors: 4

Inhibition of rat brain monoamine oxidase activity by indole 2,3 dione (Isatin) and its structural analogs.

Journal: Biogenic Amines (1994), 10: 473-485.

Authors: 4

Inhibition of glucose transport in human erythrocytes by 2,3 di-indoline (Isatin).

Journal: Experientia (1994), 50: 833-836.

Authors: 4

In vivo effects of isatin on certain enzymes, lipids and serotogenic system of rat brain.

Journal: Indian J Med Res (1994), 100: 246-250.

Authors: 3

Expression of brush border enzymes in ethanol fed rat intestine.

Journal: Indian J Med Res (1994), 100: 289-294.

Authors: 3

Apical transport of surfactant like particles in CaCO2 cells occurs para-cellularly.

Journal: Am J Physiol (1995) 268: C 1401- 1413.

Authors: 5

Two intestinal alkaline phosphatase isoforms with different carboxyl terminal peptides are both membrane bound by a glycan phosphatidylinositol linkages.

Journal: J Biol Chem (1995), 270: 11935-11940.

Authors: 3

Effect of chronic ethanol administration on macromolecular absorption in rats fed low and high protein diets.

Journal: Ann Nutr Metabol (1995), 39: 152-158.

Authors: 4

Dietary protein regimens and chronic ethanol administration effects on Na and proton dependent solute uptake in rat intestine.

Journal: Alcohol (1995), 12: 459-462.

Authors: 4

Changes in tubular membrane glycosylation in diabetic and hormone treated rat kidneys.

Journal: Indian J Exp Biol (1996), 34: 782-785.

Authors: 3

Dietary effects on brush border membrane composition and enzyme activities in rat intestine.

Journal: Ann Nutr Metabol (1996), 40: 269- 276.

Authors: 4

A competitive inhibitor of lysine uptake in rat intestine.

Journal: Indian J Biochem Biophys (1996), 133: 519-522.

Authors: 4

Differential effects of Lindane on intestinal functions in normal and malnourished rats.

Journal: Pest Biochem Physiol (1997) 57, 192-199.

Authors: 3

Effect of chronic ethanol feeding on intestinal alkaline phosphatase activity in rats.

Journal: Indian J Med Res (1998), 107: 118-122.

Authors: 4

Ethanol effects on lipid per-oxidation and glutathione mediated defence in rats fed dietary fats.

Journal: Alcohol (1998), 15: 65-69.

Authors: 4

Harmaline inhibition of invertase activity in S. Cervesiae.

Journal: Indian J Biochem Biophys (1998) 35: 86-90.

Authors: 5

Inhibition of invertase activity in Sacromyces cervesiae by sodium ions.

Journal: Indian J Exp Biol (1998), 36: 493-496.

Authors: 4

Functional role of sialic acid in IgG binding to microvillus membranes in neonatal rat intestine.

Journal: Biol Neonate (1999) 76: 55- 64.

Authors: 4

Binding of pili from uropathogenic E. coli to membranes secreted by human colonocytes and enterocytes.

Journal: Infection and Immunity (1999), 67:61-63.

Authors: 6

Ethanol effects on intestinal functions in Giardia lamblia infected rats.

Journal: J Clin Biochem Nutr (1999), 26: 17-25.

Authors: 4

IgG binding to microvillus membranes in developing rat intestine.

Journal: Indian J Biochem Biophys (1999) 36: 252-256.

Authors: 5

Role of intestinal surfactant like-particles as a potential reservoir of uropathogenic Escherichia coli.

Journal: Biochim Biophys Acta (2000), 1523: 49-57.

Authors: 6

Regulation of Surfactant like particles secretion by CaCO2 cells.

Journal: Biochim Biophys Acta (2001) 1511:369-388.

Authors: 3

Formation of surfactant-like-particles in chronic ethanol fed rat intestine.

Journal: Indian J Exp Biol (2001), 39:767-771.

Authors: 4

Age related effects of Endosulfan on intestinal functions in control and protein malnourished rats.

Journal: Indian J Exp Biol (2001) 38: 249- 252.

Authors: 3

Age related effect of organochlorine insecticide lindane on intestinal brush border membrane in rats.

Journal: Indian J Biochem Biophys (2001), 38: 249-252.

Authors: 3

Analysis of brush border membrane enzymes in proximal Jejunum of portal hypertensive rats.

Journal: J Gastroenterol (2001), 36: 407-409.

Authors: 3

Secreted intestinal surfactant like particles interact with cell membranes and extra cellular matrix proteins in rats.

Journal: J Physiol (London) (2002), 542: 237-44.

Authors: 3

Changes in the chemical composition of surfactant-like-particles secreted by small intestine in response to dietary fats.

Journal: Lipids (2002), 37:463-68.

Authors: 4

Effect of harmaline on intestinal brush border sucrase activity in rat intestine.

Journal: Indian J Biochem Biophys (2002), 39: 119-123.

Authors: 3

Effect of Zinc on hepatic Lipid peroxidation and anti-oxidative enzymes in ethanol fed rats.

Journal: J Appl Toxicol (2002) 22: 207-210.

Authors: 4

Rat enterocytes secrete SLPs containing alkaline phosphatase and cubilin in response to corn oil feeding.

Journal: Am J Physiol (2003) 285: G433- G441.

Authors: 3

Effect of protein synthesis inhibitors on alkaline phosphatase secretion by enterocytes in rat intestine.

Journal: Indian J Gastroenterol (2004), 23: 175-177.

Authors: 2

Ethanol induced changes in lipid composition of intestinal microvillus membranes in rats fed different dietary fats.

Journal: Ann Nutr Metabol (2004), 48: 221-227.

Authors: 5

Effect of prenatal ethanol administration on microvillus membrane glycosylation in developing rat intestine.

Journal: Indian J Biochem Biophys (2004), 41: 116-119.

Authors: 4

Effect of prenatal exposure of ethanol on postnatal development of intestinal transport functions in rats.

Journal: Eur J Nutr (2004), 43:109- 115.

Authors: 3

Prenatal ethanol administration effects on IgG absorption in developing rat intestine.

Journal: Biol Neonate (2004), 86: 10-14.

Authors: 4

Developmental changes in intestinal brush border enzymes of rats prenatally exposed to ethanol.

Journal: Indian J Biochem Biophys (2004) 41: 221-226

Authors: 4

Postnatal development of alcohol dehydrogenase in liver and intestine of rats exposed to ethanol in utero.

Journal: Indian J Med Res (2005), 121: 39-45.

Authors: 4

Expression of brush border enzymes in response to lead exposure in rat intestine.

Journal: J Appl Toxicol (2005), 25: 361-364.

Authors: 2

In vitro translation of RNA to lactase during postnatal development of rat intestine.

Journal: J Biosciences (2005), 30: 183-189.

Authors: 4

Role of zinc ingestion on lipid peroxidation and antioxidative enzymes in intestine of ethanol fed rats.

Journal: Biol Trace Elem Res (2004), 100: 247-258.

Authors: 4

Giardia lamblia: Expression of alkaline phosphatase activity in infected rat intestine.

Journal: Exp Parasitol (2005), 110:91-95.

Authors: 4

Influence of zinc on hepatic trace elements and biokinetics of Zn in ethanol treated rats.

Journal: Indian J Exp Biol (2005), 43:259-263.

Authors: 5

Molecular basis of Nutrient absorption from intestine.

Journal: Pb Univ Res J (2005), 55: 7-12

Authors: 2

Effect of feeding Nickel on the expression of brush border enzymes in rat intestine.

Journal: J Appl Toxicol (2006) 26: 397-401

Authors: 3

Characteristics and physiological role of SurfactantLike-particles secreted by enterocytes.

Journal: Indian J Exp Biol (2006) 44: 519-525

Authors: 3

Intestinal alkaline phosphatase secretion in oil fed rats.

Journal: Digest.Diseases Sciences (2007) 52: 665-670.

Authors: 5

Susceptibility of brush border lactase to luminal proteases in developing rat intestine.

Journal: Indian J Gastroenterology (2006)25: 179-181.

Authors: 3

Hypolactasia as the molecular basis of lactose intolerance

Journal: Indian J Biochem Biophys.(2006) 43:267-274

Authors: 3

The profile of oxidant systems and lipid per-oxidation across crypt-villus axis in rat intestine.

Journal: Digestive Diseases and Sciences (2007) 52: 1844.

Authors: 2

Effect of tannic acid on brush border disaccharidases in mammalian intestine.

Journal: Indian J Exp.Biology (2007) 45: 353-358.

Authors: 3

Gallic acid inhibits disaccharidases in mammalian intestine.

Journal: Nutrition Research (2007), 27: 235-240.

Authors: 3

Effect of sub chronic feeding of iron on the development of brush border enzymes in rat intestine.

Journal: Toxicol MechanismsMethods,(2007) 17: 393-399.

Authors: 3

Evaluation of the kinetic properties of folate transport system in intestinal epithelium during experimental ethanol ingestion.

Journal: Molecular Cell Biochemistry (2007), 304: 365-371.

Authors: 3

Downregulation of reduced folate carrier may result in folate malabsorption across brush border membrane during experimental alcoholism.

Journal: FEBS Journal (2007) 274:6317-6328

Authors: 6

Immunoregulatory role of intestinal surface like particles during Salmonella typhimurium

Journal: Int.J.Biol. Sci (2007) 3 : 446-454.

Authors: 5

Effect of zinc on hepatic drug metabolism under ethanol toxicity.

Journal: Drug Chem Toxicity (2008) 31: 163-173.

Authors: 4

Hormone induced changes in lactase expression 16 in suckling rat intestine.

Journal: Mol. Cell Biochem (2008) 312: 11-16.

Authors: 3

Hormone induced changes in lactase glycosylation in developing rat intestine.

Journal: Mol Cell Biochem (2008), 318: 183-190.

Authors: 3

Effect of sodium ions on pH dependent conformational changes in sucrase-isomaltase in mice intestine.

Journal: Indian J Biochem Biophys (2008), 45: 399-403.

Authors: 4

Effect of maternal diabetes on postnatal development of brush border enzymes and transport systems in rat intestine.

Journal: J Pediatric Gastro Nutr (2009), 49: 8-15.

Authors: 3

Subacute effects of Carbofuran on enzyme functions in rat small intestine.

Journal: Toxicol Mechanisms & Methods (2009), 19: 141-147.

Authors: 3

Effect of fat feeding on pro- oxidant and anti oxidant enzyme systems of rat intestine: Possible role in turn over of enterocytes.

Journal: Digest Diseases & Sciences, (2009) 54: 1229-1236.

Authors: 5

Ethanol induced changes in glycosylation of mucins in rat intestine.

Journal: Annals of Gastroenterology,22 (2009), 178-83.

Authors: 2

Kinetic characteristics of brush border sucrase activation by sodium ions in mice intestine.

Journal: Indian J Exp.Biol. (2009), 47: 811-15

Authors: 3

Inhibition of brush border sucrase by polyphenols in mice intestine.

Journal: Bioscience Reports (2010) 30: 111-117

Authors: 4

Dietary fat feeding alters lipid peroxidation in Surfactant-like particles secreted by rat small intestine.

Journal: Gastroenterol Res, (2009) 2: 91-99.

Authors: 3

A shift in microvillus membrane fucosylation to sialylation by ethanol ingestion in rat intestine.

Journal: Mol.Cellular Biochem (2009) 331: 19-25

Authors: 2

Effect of gallic acid on alkaline phosphatase and peptidase activities in rat intestine.

Journal: Indian J Biochem Biophys (2009), 46: 378-82.

Authors: 2

Ethanol induced changes in Lipid-peroxidaton of enterocytes, across the crypt-villus axis in rat intestine.

Journal: Indian J Gastroenterology (2010) 29:17-21

Authors: 5

The effects of ethanol administration on brush border membrane glycolipids in rat intestine.

Journal: Alcohol (2010), 44:1515-22.

Authors: 2

Influence of Surfactant like particles on differential activation of secretory signalling molecules during Salmonella typhimurium infection.

Journal: J Food Safety, (2010), 30: 455-69.

Authors: 5

Modulation of lipid per- oxidation and anti 17 Oxidant enzyme systems in rat intestine by sub chronic fluoride and ethanol administration.

Journal: Alcohol (2011), 45: 663-72.

Authors: 3

Carbofuran administration induces genotoxic effects in epithelial cells across crypt-villus axis in rat intestine.

Journal: Pesticide Biochem Physiol (2011), 100: 280-83

Authors: 3

The effect of C/T-1390 cis Acting regulatory variant on the expression and activity of lactase in Indian children and, its implication in early screening of adult type hypolactasia.

Journal: Clinica Chimica Acta (2011), 412: 1924-30.

Authors: 4

Modulation of intestinal brush border membrane chemical composition during postnatal development in rats: Effect of gestational diabetes.

Journal: Indian J Exp.Biology (2012) 50: 45-50.

Authors: 3

Gestational diabetes affects postnatal development of transport and enzyme functions in rat intestine.

Journal: Molecular Cell Biochem (2012) 36: 71-77.

Authors: 4

Adult type Hypolactasia: A genetic perspective.

Journal: J Pediatric Biochem. (2012), 2: 143-151.

Authors: 5

Correlation of G/A-22018 single nucleotide polymorphism with lactase activity and its usefulness in improving, diagnosis of adult type hypolactasia, among north Indian children.

Journal: Gene & Nutrition (2013) 8: 145-51

Authors: 5

Inhibition of Dextransucrase activity in Streptococcus mutans by polyphenolics.

Journal: Indian J Biochem Biophys. (2013), 50: 48-53

Authors: 3

Effects of fluoride and ethanol administration lipid per-oxidation systems in the rat brain.

Journal: Indian J Exp. Biology (2013), 51: 249-55.

Authors: 3

In vitro effects of ethanol on intestinal epithelial cell glycosylation in rats.

Journal: J Nutr Food Sci (2013) 3: 204-07.

Authors: 3

Ethanol and age enhances fluoride toxicity through oxidative stress and mitochondrial dysfunctions in rat intestine.

Journal: Molecular Cell Biochem (2013) 384: 251-62.

Authors: 3

Lactase genetic polymorphisms and celiac disease: A cohort study.

Journal: Annals Human Biology (2014) 1-4.

Authors: 5

Invited Lectures and Chairperson-ships
Attended Meeting

on Federation of American Societies of Experimental Biology meeting, Atlantic City New Jersey (USA)

Attended Meeting

on American Biological Chemists Meeting, Saint-Paul, Minneapolis (USA)

Attended Conference

on XII Latin Biochemistry Congress, Bordeaux, France

Attended Symposium

on 2nd European Molecular Biology Organization Symposium on Membrane Biology, Heidelberg, Germany

Attended Meeting

on Annual Meeting of the British Physiological Society, Kings College, University of London, England

Attended Meeting

on Annual Meeting Federation of American Societies for Experimental Biology, Chicago, USA

Attended International Symposium

on International Symposium on 25 years of research on Brush Border Membrane and Sodium Coupled Ion Transport. Aussois, France

Attended Conference

on Summer Research Conference of Federation of American Societies for Experimental Biology in Gastroenterology - Cellular and Molecular Biology Concepts” Copper Mountains, Colorado (USA)

Others
Research interests: Membrane Enzymes & Transport Systems, Surface Oligosaccharides and Membrane receptors, Nutrition & Environmental Toxicants, Structure & Functions of Small Intestine
Experience Abroad: *Visiting Research Professor at Washington University, Medical School, St., Louis, USA. (1990-1992 and 1999-2001). *Visiting Research Professor at University of Oklahoma, Health Sciences Centre, Oklahoma City, USA. (1981-1985). *Associate Investigator at University of Paris-Sud, Orsay, France. (1975-1977). *Research Associate at University of Puerto Rico Medical School, San Jaun, Puerto Rico, USA. (1972-1975)
Ph.D. Theses Supervised: Biochemical mechanisms involved in cadmium toxicity in rat pancreas and its effects on zinc and chromium metabolism (1981)- Vijay Lyall
Ph.D. Theses Supervised: Certain aspects of biologic and immunologic effects of technical grade DDT in rhesus monkeys (1981)- Neeraj Agarwal
Ph.D. Theses Supervised: Biochemical mechanisms involved in the transport of oxalate and its possible role in urolithiasis (1982)- Shakeel Farooqui
Ph.D. Theses Supervised: Biochemical studies on the effects of DDT administration on rat intestinal epithelium (1983)- Pradeep K Dudeja
Ph.D. Theses Supervised: Role of ascorbic acid in the intestinal brush border membrane structure and function (1983)- Rakesh Dulloo.
Ph.D. Theses Supervised: A study of biochemical and immunological aspects in experimental giardiasis (1982)- Rhadha Krishan.
Ph.D. Theses Supervised: Studies on the molecular basis of protein absorption in suckling rat intestine (1991)- Harjeet Singh.
Ph.D. Theses Supervised: Studies on glycosylation of intestinal epithelium in rats: Effect of hormones and under nutrition (1991)- V.M.S.Jaishwal.
Ph.D. Theses Supervised: Studies on epithelial cell surface glycosylation in mice intestine: Effect of different nutritional regimens (1992)-Reena Gupta.
Ph.D. Theses Supervised: Effect of chronic ethanol ingestion on intestinal microvillus membrane in rats with special reference to epithelial cell surface glycosylation and macro molecular uptake (1994)-Jyotdeep Kaur.
Ph.D. Theses Supervised: Biochemical studies on the mechanism of action of Isatin: A potent anticonvulsant (1994)-Rakesh Kumar.
Ph.D. Theses Supervised: Isatin inter-actions with sodium dependent enzyme and transport systems in experimental animals (1994)-Latif Masouvi.
Ph.D. Theses Supervised: Studies on the functional adaptation of intestine to dietary constituents in starved rats (1995- Sarbjit Kaur.
Ph.D. Theses Supervised: Studies on the effect of ethanol on rat intestinal epithelium following dietary fat manipulations (1995) Meenu Kaur.
Ph.D. Theses Supervised: Studies on the effect of endosulfan and dieldrin on intestinal structure and functions in rats (1997)- Sumeet Labana.
Ph.D. Theses Supervised: Studies on the molecular mechanisms of intestinal mal-absorption in Giardia lamblia infected and Ethanol fed rats (1999)- Nidhi.
Ph.D. Theses Supervised: Studies on the expression of IgG receptor in developing rat intestine (2000)-R.K.Gill.
Ph.D. Theses Supervised: Effect of ethanol and dietary fats on the secretion and characterization of surfactant like particles in rat intestine (2000)- Seema Kumar.
Ph.D. Theses Supervised: Role of Zinc in the metabolic effects of ethanol in rat liver and intestine (2001)- Ashima.
Ph.D. Theses Supervised: Studies on the effects of prenatal ethanol exposure on intestinal development in rats (2001)- Sonali Bhalla
Ph.D. Theses Supervised: Studies on the regulation of intestinal lactase gene in hypolactasia in adult rats (2003)- Jaspreet Kaur.
Ph.D. Theses Supervised: Immuno regulatory properties of surfactant like particles from rat intestine (2003)-Mohd Hanif.
Ph.D. Theses Supervised: Molecular mechanisms of S.typhimurium infection in rabbit ileum (2006)-R.Verma
Ph.D. Theses Supervised: Studies on postnatal development of lactase and intestinal glycosylation in rats (2007)- Kamajit Kaur.
Ph.D. Theses Supervised: Studies on the characterization and functions of Surfactant-like-Particles in response to dietary fats(2008)-Aasma Turan.
Ph.D. Theses Supervised: Effect of Chronic ethanol ingestion on intestinal glycosylation in rats (2008)-Ravneet Grewal.
Ph.D. Theses Supervised: Effect of maternal diabetes on postnatal development of intestinal functions in the rat. (2009)- Ruchi Sharma.
Ph.D. Theses Supervised: Metal ion interactions and pH effects on purified intestinal brush border sucrase from mice Intestine (2009)-Sheffalli Gupta
Ph.D. Theses Supervised: Effect of Carbofuran on structure and functions of rat intestine (2009)-Nidhi Gera.
Ph.D. Theses Supervised: Study of certain lipid metabolising enzymes, lipoproteins and homocysteine in rat arterial Tissue after monosodium glutamate administration (2011).
Ph.D. Theses Supervised: Intestinal lactase regulation and role of single nucleotide polymorphism (SNP’s) associated with LCT gene in hypolactasia among Indian population. (2012) RAH Kuchay.
Ph.D. Theses Supervised: . Effect of chronic fluoride ingestion and aging on metabolic activities of intestine and brain in ethanol fed rats. (2012) SS Chauhan.
Ph.D. Theses Supervised: Studies on the characterization of disaccharidases in Sacchromyces Cervisiae under different stress conditions.(2013)- Smita
Reviewed Research Grant Proposals: Department of Science and Technology Govt. of India, New Delhi.
Reviewed Research Grant Proposals: Department of Science & Technology, Chandigarh.
Reviewed Research Grant Proposals: Indian Council of Medical Research, New Delhi.
Project Work
Professional Association
Member, Member of the Senate, Panjab University, Chandigarh. November 2000-October 2004, November 2004 to October 2008 and November 2012-October 2016.
Member, Member of the National Executive Committee of the Society of Biological Chemists (India) for the year 1979-1981 and 1986-88.
Member, Member Board of Finance, Panjab University, Chandigarh for the year 2004.
Member, Member Project Review Committee, Department of Science and Technology, Govt of India.
Member, Member CSIR, Project Review Committee/and Selection Committees for the recruitment of Scientists.
Member, Member Research Degree Committees, Undergraduate and Postgraduate studies of various Universities in India.
Chief Co-ordinator, Centre for Emerging Areas in Science & Technology, Panjab University, Chandigarh
Vice-President, Society of Biological Chemists (India)